The Grand Challenges family of initiatives fosters innovation to solve key health and development problems. See below for Grand Challenges and related grant opportunities.
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Epidemic threats are increasing in their frequency, intensity, and severity – yet the world remains woefully exposed and unprepared. Grand Challenges Senegal is soliciting proposals from innovators working across Africa and African scientists in the diaspora on interventions to enhance epidemic intelligence, surveillance, and outbreak response.
Mathematical modeling and analytics are valuable tools to inform policy and programmatic decisions, and there have been many successful examples in global health using disease burden estimation, modeling, and forecasting. It has become increasingly clear that these approaches will need to incorporate a gender lens, either because women and girls comprise a greater fraction of the remaining burden, or because they hold the keys to a more efficient solution. This RFP seeks innovative approaches to modeling of women's health issues or of broader health topics that incorporate a gender lens.
Genomic surveillance of pathogens can provide information about pathogen evolution and insight into the genetic basis of changes in virulence or resistance to interventions. During the COVID-19 pandemic, genomic surveillance for SARS-CoV-2 was established by many countries, including countries in Asia. In response to this request for proposals, we seek projects from investigators in South and Southeast Asia that address one - or both - of the following goals: 1) Design and pilot a genomic surveillance program for a priority pathogen (other than SARS-CoV-2) and 2) Develop capacity for Immunology and Immune Sequencing of SARS-CoV-2 to inform Epidemic Response.
This Challenge seeks innovative approaches to enhance climate adaptation for agriculture in Africa in ways that link directly with and strengthen the ecosystem of local actors and institutions. Specifically, the objective of the challenge will be to support innovations that strengthen agriculture-related risk management processes and adaptation prioritization, planning, and investment, through intra-Africa research collaboration on data, data science, and modeling.
This Challenge seeks innovations that contribute to the development of safe and effective non-hormonal contraceptives that meet the needs and interests of women and that address key barriers in accessing and using currently available methods. We are seeking non-hormonal contraceptives that are easy to access, discreet, convenient, and non-invasive. Additionally, it is important that these methods have tolerable side effects and do not impact the menstrual cycle.
Grand Challenges Canada's Stars in Global Health program seeks applications addressing human health impacts of climate change in low- and middle-income countries. These innovative solutions are expected to address the adaptation gaps and build resilience against the effects of climate change on the human health and wellbeing of underserved communities.