The Grand Challenges family of initiatives fosters innovation to solve key health and development problems. See below for Grand Challenges and related grant opportunities.
While mathematical modeling approaches have been used to understand malaria epidemiology and the potential impact of antimalarial interventions for some time, National Malaria Control Programs (NMCPs) across sub-Saharan Africa are showing a growing interest in working with modeling units to shape their National Strategic Plans and Global Fund applications, as well to evaluate the ongoing impact of control programs. This RFP seeks innovative approaches to building a stronger malaria mathematical modeling ecosystem in sub-Saharan Africa.
Digital health is revolutionizing the landscape of global healthcare. Solutions such as telemedicine, electronic medical records, and digitally enabled devices help to provide accessible, high-quality care around the world. We seek patient-facing digital health services for pregnant women that have been developed and are actively being provided in sub-Saharan Africa (SSA). We will consider proposals for services that can support or contribute to our ARS vision via digital applications.
The elimination of neglected tropical diseases (NTDs) is feasible but its progress is hindered by a paucity of effective intervention tools, the suboptimal implementation of existing tools, or both. We see an opportunity to identify and demonstrate feasibility of new applications of cutting-edge technologies used by other disease areas to address the challenges faced by national NTD programs and accelerate the elimination of NTDs.
The scale and scope of the COVID-19 pandemic have reiterated the need for access to and analysis of timely accurate health data to support the implementation of control measures and to guide health interventions and evidence-based practices. The supporting infrastructures and capacities through which researchers access and analyze these data, however, vary greatly. For several reasons, researchers in the Global South often are skeptical of broad calls for data sharing when they are left out of the analysis and results interpretation.
Recognizing barriers for adoption of next-generation sequencing in global health, the Bill & Melinda Gates Foundation has partnered with the Chan Zuckerberg Biohub and the Chan Zuckerberg Initiative to enable populations in low- and middle-resource settings to benefit from cutting-edge pathogen detection, discovery and characterization. This partnership will provide highly specialized training in biosample preparation and sequencing to technical staff from awardee global health centers.